Monday, May 7, 2012

GPAT Paper, 2012 | Find out GPAT 2012 question Paper with key answers

GPAT Paper, 2012 | Find out GPAT 2012 question Paper with key answers


GPAT Paper, 2012 | Find out GPAT 2012 question Paper with key answers

Posted: 06 May 2012 09:33 AM PDT

GPAT-2012 PAPER

{Answers are on the end page of question Paper}


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Government invites Pharmacist by Director Medical Education & Research- 7 posts - Freshers may apply

Posted: 06 May 2012 06:20 AM PDT

Govt. of Haryana has set up a new Medical College at Khanpur Kalan in District Sonepat. It is a Govt. College for girls. Posts of ancillary services are lying vacant on regular basis in BPS Government Medical College for Women, Khanpur Kalan, Sonepat. Applications on the prescribed form are invited for the following posts of ancillary services:-

Post: Dispensary Services- Pharmacist 7 (5 Gen, 1SC, 1BCA)


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Freshers M.Pharm/M.Sc invited for post of Global Regulatory Affairs Labeling Professional I and II @ Novartis Healthcare

Posted: 06 May 2012 05:55 AM PDT

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.


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Abbott in invites B. Pharma / M Pharma for Manager - TPM in Manufacturing

Posted: 06 May 2012 05:43 AM PDT

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.


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PPIC Manager for Pharma API in Naprod Lifesciences

Posted: 06 May 2012 05:31 AM PDT

Naprod’s vision is to become a world class player in oncology through excellence in innovation, discovery of new manufacturing processes / drug delivery mechanisms and consistently high quality of production. We commenced operations in 1994 with the inauguration of our ultra-modern facility for the production of generics and formulations for oncology and other therapeutic applications. We are one of the pioneers in India in lyophilization.


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Job as Quality Assurance Executive - Palghar in Strides Arcolab

Posted: 06 May 2012 05:12 AM PDT

At Strides, the truly global pharma company, each day is more exciting - you never know from which part of the world the challenge may come!


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Require Assistant - Production in Flamingo Pharma - 5 Vacancies

Posted: 06 May 2012 04:45 AM PDT

Flamingo Pharmaceuticals Ltd. is a quality driven pharmaceutical company with an experience of over two decades in global markets, exporting to 52 countries and having Rs.200 crores+ turnover. Flamingo has WHO-GMP/UK MHRA certified 100% EOU unit.


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Vacancy for post of Manager - Clinical Budget Analysis in Abbott

Posted: 06 May 2012 04:32 AM PDT

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.


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Requirement of Executive / officer - IPR (Intellectual Property) (API - R & D) @ Zydus Cadila

Posted: 06 May 2012 04:17 AM PDT

A REVIEW ON NEW INNOVATIONS AND TECHNOLOGIES IN THE FORMULATION OF ORALLY DISINTEGRATING TABLETS

Posted: 05 May 2012 11:30 PM PDT

ABOUT AUTHORS:
YASWANTH ALLAMNENI1*, NAVYA ALLAMNENI2, R AMARNATH1, T RAMASWAMY CHOWDARY1, V SATYANARAYANA1, K VENKATESWARA RAO1

1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar, Andhra Pradesh – 509228.
2Department of Pharmaceutical Technology, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Guntur,
Andhra Pradesh, India.
*yaswanthallamneni@gmail.com

ABSTRACT
The main aim of this article was to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects.Over the past three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. Orally disintegrating tablets are also called as orodispersible, quick disintegrating, mouth dissolving, fast disintegrating, rapid dissolving tablets, porous tablets, and rapimelts.Orally disintegrating systems have carved a niche amongst the oral drug delivery systems due to the highest component of compliance they enjoy in patients especially the geriatrics and pediatrics. However, of all the above terms, USP approved these dosage forms as ODTs.  These tablets are distinguished from conventional sublingual tablets, lozenges, and buccal tablets which require more than a minute to dissolve in the mouth. According to the recently issued draft guidance for Industry of orally disintegrating tablets, FDA specifically recommends that, in addition to the original definition for an ODT, ODTs be considered solid oral preparations that disintegrate rapidly in the oral cavity, with an in vitro disintegration time of approximately 30 sec or less according to the united states pharmacopoeia (USP) disintegration method or alternative. ODTs release drug in the mouth for absorption through local oromucosal tissues and through pregastric (e.g., oral cavity, pharynx, and oesophagus), gastric (i.e., stomach) and post gastric (e.g. .small and large intestines) segments of the gastrointestinal tract.


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